[[File:Cpord.jpg|thumb|The CPORD flag.|200x200px]]
'''Cytochrome PORD (CPORD)''' is an [[intersex]] conditionvariation that effects both [[CTM]] and [[CTF]] individuals alike. This conditionvariation is characterized by a mutation in horomoneshormones, which causes onereduced to gain [[hypogonadism]], and have a lackproduction of testosteronesteroid and estrogen alikehormones. It is unknown how common this conditionvariation is, as only 65 cases have been reported.<ref>{{Archive|Site=web|URL=https://medlineplus.gov/genetics/condition/cytochrome-p450-oxidoreductase-deficiency/}}</ref>
For those with this conditionvariation, [[Ambiguous Genitalia|ambiguous genitals]] and infertility is common amongst both CTM and CTF individuals.
For CTF individuals, amenorrhea, [[PCOS|ovarian cysts]], and [[hyperandrogenism]] is common. Because of this, CTF individuals tend to have masculinized traits that cause irregular menstruation, acne, excessive body hair, and weight gain.
For CTM individuals, [[AMAB Hypogonadism|AMAB hypogonadism]] occurs.<ref>https://en.wikipedia.org/wiki/Cytochrome_P450_oxidoreductase_deficiency</ref>
It is important to note that not all the symptoms listed in this page are guaranteed to occur in someone with this condition, as someone may only experience one or several of these symptoms, yet still hold the condition.
== Antley-Bixler Syndrome ==
'''Antley-Bixler Syndrome (ABS)''' is know as the more severe version of Cytochrome PORD. The symptoms are more prominent and dramatic in nature, and are often more obvious than CPORD.
Those with this conditionvariation may or may not experience the symptoms of CPORD, however they do have their own exclusive symptoms that are listed below. This conditionvariation can effect both CTF and CTM peopleindividuals, just as CPORD can.
Symptoms include disorderedanal steroidogenesisabnormalities, cardiac malformations, skeletal abnormalities, locked elbows, unusually long fingers, bowed thigh bones, a flattened mid-face, a prominent forehead, bulging eyes, low set ears, unusuallya longclosed fingers,off locked elbowsnasal, intellectual disabilities, and slowed development are prominent. They also tend to either have ambiguous genitals or to be on the [[agenital]] spectrum, and are infertile<ref>https://rarediseases.info.nih.gov/diseases/5826/antley-bixler-syndrome</ref>
Those that are CTF may have [[Agenital|a closed off vagina.]]<ref>https://en.wikipedia.org/wiki/Antley%E2%80%93Bixler_syndrome</ref><ref>https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/antley-bixler-syndrome</ref>
== Causes ==
This condition is caused by mutations in the POR gene, a gene that provides instructions for enzymes that play a critical role in steroid horomones. Because of this mutation, horomones such as testosterone and estrogen become very low in production, and don't balance correctly within the body. ▼
== PregnancyCauses ==
▲This conditionvariation is caused by mutations in the POR gene, a gene that provides instructions for enzymes that play a critical role in steroid horomoneshormones. Because of this mutation, horomoneshormones such as testosterone and estrogen become very low in production, and don't balance correctly within the body.
== Pregnancy==
Individuals who are pregnant with children who have CPORD and/or ABS tend to develop some symptoms themselves while the baby is forming. This includes development of excessive body hair, acne, and a deepening voice. These changes slowly go away after the baby is delivered.
The reasoning for this is due to horomonalhormonal disturbance effecting not only the baby, but the carrier of the baby as well during development.
The CPORD flag was coined by [[User:Reign of the breadsticcs|Reign of the breadsticcs]] on May 7th of 2021. It has no confirmed meaning.
== Resources ==
* https://medlineplus.gov/genetics/condition/cytochrome-p450-oxidoreductase-deficiency/#causes
*The CPORD flag was coined by [[User:Reign of the breadsticcs|Reign of the breadsticcs]] on May 7th of 2021. It has no confirmed meaning.<ref>{{Archive|Site=web|URL=https://lgbta.wikia.org/f/p/4400000000000137332/r/4400000000000449105}}</ref>
==References==
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[[Category:Intersex Traits]]
[[Category:TerminologyVerified Resources]]
[[Category:Pages With No History Section]]
[[Category:Sex Category]]
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