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    XXYY Syndrome: Difference between revisions

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    [[File:Davpdk2-7216a1e4-f283-448a-8ecf-689985e43c20.png|thumb|220x220px|The XXYY flag.<ref>https://www.deviantart.com/pride-flags/art/XXYY-Syndrome-657913826</ref>]]
    [[File:Davpdk2-7216a1e4-f283-448a-8ecf-689985e43c20.png|thumb|220x220px|The XXYY syndrome flag.<ref>https://www.deviantart.com/pride-flags/art/XXYY-Syndrome-657913826</ref>]]
    [[File:Xxyy.png|thumb|218x218px|Alternate XXYY syndrome flag.]]
    '''XXYY''' or '''48,XXYY syndrome''' or '''48,XXYY''' is a rare [[CTM]] [[intersex]] trait occurring in approximately 1 in 18,000 to 1 in 40,000 people [[Assigned Gender|assigned male at birth]].<ref>https://ghr.nlm.nih.gov/condition/48xxyy-syndrome#</ref> It is a chromosomal condition that causes them to have an extra X and an extra Y chromosome (XXYY). It may be considered a variant of [[Klinefelter Syndrome|Klinefelter syndrome]].
    '''XXYY''' or '''48,XXYY syndrome''' or '''48,XXYY''' is a rare [[CTM]] [[intersex]] trait occurring in approximately 1 in 18,000 to 1 in 40,000 people [[Assigned Gender|assigned male at birth]].<ref>https://ghr.nlm.nih.gov/condition/48xxyy-syndrome#</ref> It is a chromosomal condition that causes them to have an extra X and an extra Y chromosome (XXYY). It may be considered a variant of [[Klinefelter Syndrome|Klinefelter syndrome]].


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    == History ==
    == History ==
    The first published report of a boy with a 48,XXYY karyotype was by Sylfest Muldal and Charles H. Ockey in Manchester, England in 1960. It was described in a 15-year-old mentally challenged boy who showed signs of Klinefelter syndrome; however, chromosome testing revealed 48,XXYY instead of the 47, XXY arrangement known to cause [[Klinefelter Syndrome|Klinefelter syndrome]]. Because of this, 48,XXYY syndrome was originally considered a variation of Klinefelter syndrome.
    The first published report of an individual with a 48,XXYY karyotype was an [[AMAB]] individual by Sylfest Muldal and Charles H. Ockey in Manchester, England in 1960. It was described in a 15-year-old mentally challenged boy who showed signs of Klinefelter syndrome; however, chromosome testing revealed 48,XXYY instead of the 47, XXY arrangement known to cause [[Klinefelter Syndrome|Klinefelter syndrome]]. Because of this, 48,XXYY syndrome was originally considered a variation of Klinefelter syndrome.


    == Flag ==
    == Flag ==
    The flag was coined by Deviantart user Pride-Flags on January 16th of 2017. It has no confirmed meaning.
    The flag was coined by Deviantart user Pride-Flags on January 16th of 2017. It has no confirmed meaning.

    The second flag was coined by Cryptocrew, specifically Adora, on May 4th of 2021. It uses some of the same colors of the original flag, but with added meaning. Dark blue represents being assigned male, light blue represents masculinity, white represents community and diversity, purple represents the intersex spectrum, light pink represents a lack of testosterone production, and dark pink represents feminine and androgynous traits. The design is made up of two X's and two Y's to represent the condition as a whole.


    == Resources ==
    == Resources ==
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