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:''{{Distinguish|XXYY Syndrome|XXXYY Syndrome|XYYYY Syndrome|XYYY Syndrome}}''
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Those with this variation tend to have facial dysmorphism, mild microcephaly, limitation of supination at the elbows, delayed bone age, and moderate [[Neurodivergent|intellectual disability]]<ref>https://pubmed.ncbi.nlm.nih.gov/8330452/</ref> This variation is often considered a subset of [[Klinefelter Syndrome|kilnefelter syndrome]]. If these symptoms cause any physical struggles, they may be classified as physically [[disabled]].
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