[[File:Opitz GBBB.jpg|thumb|200x200px|The Opitz G/BBB Syndrome flag.]]
'''Opitz G/BBB syndrome''' is a conditionsyndrome that - in some cases - may be considered an [[intersex]] conditionvariation, although many would say it ''causes'' intersex conditionstraits rather than being one in of itself. Opitz G/BBB syndrome is thought to affect 1 in 10,000 to 50,000 [[CTM]] or [[AMAB]] individuals, although, according to proffessionals, it is likely that this conditionsyndrome is underdiagnosed.
This conditionsyndrome can cause a [[Agenital|missing or undescended testicle]], [[hypospadias]], an underdeveloped scrotum, and/or a scrotum divided into two lobes. This may cause urinal issues.
This conditionsyndrome often comes with defects in the voice box, windpipe, or esophagus which, in many cases, causes breathing and swallowing abnormalities that can, in some cases, be life threatening. This conditionsyndrome often comes with distinct facial features, such as a prominent forehead, a thin upper lip, low ears, and a flat nasal bridge.
Studies have shown that 50% of individuals with this conditionsyndrome have autism and other mental disabilities. This often causes a delay in speech and motor skills, as well as learning disabilities. 50% also tend to have a cleft lip or cleft palate. In some rarer cases, heart defects, anal obstruction, and/or absencies between the left and right side of the brain are found.
It is important to note that not all the symptoms listed in this page are guaranteed to occur in someone with this conditionsyndrome, as someone may only experience one or several of these symptoms, yet still hold the conditionsyndrome.
== Causes ==
This conditionsyndrome can be caused by two things; mutations in the ''MID1'' gene (a gene that provides instructions for making ''midline-1'', which is a protein that binds microtubules) or changes/mutations in ''chromosome 22'', which may include the entire deletion of the chromosome in of itself.
There are some rare cases where niether of these reasonings apply, and it is unknown how those without these two causes gains this conditionsyndrome.
== Flag ==
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