[[File:Kallman syndrome.jpg|thumb|200x200px|The Kallman Syndrome flag.]]
'''Kallman Syndrome''' is an [[intersex]] conditionvariation that can effect both [[CTM]] and [[CTF]] peopleindividuals. It is estimated to occur in 1 in everevery 30,000 [[AMAB]] individuals, and 1 in every 120,000 [[AFAB]] individuals, meaning it is more common amongst AMAB peopleindividuals.<ref>https://en.wikipedia.org/wiki/Kallmann_syndrome</ref>
In CTM peopleindividuals, symptoms include [[Agenital|a micropenis, cryptorchidism]], and/or [[AMAB Hypogonadism|AMAB hypogonadism]]. They may also fall under [[Aromatase Excess Syndrome|aromatase excess syndrome]] due to the lack of testosterone, however this is not always the case.
In CTF peopleindividuals, symptoms include [[Secondary Sex Agenesis|lack of breast growth]], unfinished puberty, lack of menstruation, and [[AFAB Hypogonadism|AFAB hypogonadism]]. They may also fall under [[hyperandrogenism]] due to the lack of estrogen, however this is not always the case.
In both CTF and CTM peopleindividuals, symptoms that may or may not occur include [[Secondary Sex Agenesis|lack of muscle definition]], a reduced or total lack of smell, neutral or complete deafness, possibility of color blindness, a missing kidney, poor coordination, hand synkinesis, a cleft lip, a split hand/foot, a shortened middle finger, and/or scoliosis.<ref>https://en.wikipedia.org/wiki/Kallmann_syndrome#Signs_and_symptoms</ref> Some of the variations may classify one with this syndrome as physically [[disabled]].
== Causes ==
Changes in more than twenty genes have been associated with Kallmann syndrome. Among the most common causes of the conditionvariation are mutations in the ''ANOS1'', ''CHD7'', ''FGF8'', ''FGFR1'', ''PROK2'', or ''PROKR2'' gene. In some cases, affected individuals have mutations in more than one of these genes.
Additionally, researchers have identified mutations in other genes that may contribute to the development and features of Kallmann syndrome, but are unlikely to cause the conditionvariation on their own.<ref>https://medlineplus.gov/genetics/condition/kallmann-syndrome/#causes</ref>
== History ==
Kallmann Syndrome was first described by name in a paper published in 1944 by Franz Josef Kallmann, a German-American geneticist.<ref>https://en.wikipedia.org/wiki/Kallmann_syndrome#History</ref>
== Flag ==
The ATR-16 Syndrome flag was coined by [[User:Reign of the breadsticcs|Reign of the breadsticcs]] on May 7th of 2021. It has no confirmed meaning.
== Resources ==
* https://en.wikipedia.org/wiki/Kallmann_syndrome
* https://medlineplus.gov/genetics/condition/kallmann-syndrome/#frequency
*https://lgbta.wikia.org/f/p/4400000000000137332/r/4400000000000449105
== References ==
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[[Category:Intersex Traits]]
[[Category:TerminologyVerified Resources]]
[[Category:Sex Category]]
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