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== References == |
== References == |
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[[Category:Sex |
[[Category:Sex Terminology]] |
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Latest revision as of 05:42, 28 June 2024
Genotypic sex or genetic sex, also referred to as chromosomal sex or karyotypic sex, is determined by the combination of sex chromosomes an individual inherits. In most mammals, including humans:[1]
- XX specifies müllerian genotypic sex (two X chromosomes).
- XY specifies wolffian genotypic sex (one X and one Y chromosome).
These sex chromosomes typically determine an individual’s biological or anatomical sex. While the X chromosome carries a wide variety of genes, the Y chromosome is shorter and contains fewer genes, including the pivotal SRY gene responsible for wolffian development.[2][3] However, there are intersex genotypes or karyotypes (intergenotypes), such as:
- 45,X/46,XY mosaicism
- Turner (X0)
- XXY (Klinefelter's)
- XYY (Jacob's)
- Triple X (XXX)
- De La Chapelle (XX)
- Swyer's (XY)
- XYYY
- Tetrasomy X (XXXX)
- XXYY
- XXYYY
- XXXYY
- XXXXY
- XYYYY
- Pentasomy X (XXXXX)
- SERKAL (XX)
Though most intergenotypic variations are often labeled as syndromes, some may consider their traits in other ways.