'''Denys-Drash Syndrome (DDS)''' is an [[intersex]] traitvariation that effects both [[CTF]] and [[CTM]] individuals. It has only around 150-200 reports, however it may be more frequent than this, just without notice . This condition is caused when one ''WT1'' gene- a gene designed(especially for connectingCTF regions of DNA together- fails to properly functionindividuals. Because of this, proteins that effect genitals and kidneys are effected during development in the womb)<ref>{{Archive|Site=web|URL=https://medlineplus. gov/genetics/condition/denys-drash-syndrome/#frequency}}</ref>▼
[[File:Denys-Drash Syndrome.jpg|thumb|Flag by Ariathatsme]]
▲'''Denys-Drash Syndrome (DDS)''' is an [[intersex]] trait that effects both [[CTF]] and [[CTM]] individuals. It has only around 150-200 reports, however it may be more frequent than this, just without notice. This condition is caused when one ''WT1'' gene- a gene designed for connecting regions of DNA together- fails to properly function. Because of this, proteins that effect genitals and kidneys are effected during development in the womb.
Those with this conditionvariation have ''diffuse glomerulosclerosis'', which is a condition that effects ones kidneys abilities to filter waste. Because of this, they have a 90% chance at gaining ''Wilms tumor'', a rare kidney cancer.<ref>{{Archive|Site=web|URL=https://medlineplus.gov/genetics/condition/denys-drash-syndrome/}}</ref>
CTM individuals with this conditionvariation may have a penis, however they often have [[Ambiguous Genitalia|ambiguous genitals]], [[Agenital|undescended testicles (cryptorchidism)]], or a vagina. Because of this, they typically are infertile and unable to bare children. They also typically have [[Gonadal Dysgenesis|gonadal dysgenesis]] and/or [[AMAB Hypogonadism|AMAB hypogonadism]] as well.
CTF individuals with this conditionvariation have a vagina, while the only noticeable trait of DDS is their kidneys. Because of this, they are often diagnosed with other kidney-related conditionsvariations, rather than with DDS.
== Frasier Syndrome ==
It is important to note that not all the symptoms listed in this page are guaranteed to occur in someone with this condition, as someone may only experience one or several of these symptoms, yet still hold the condition.
''Not to be confused with [[Fraser Syndrome]].''
'''Frasier Syndrome''' is an intersex variation that falls under DDS. It has the same cause (improper function of the ''WT1'' gene) however it is less severe. The symptoms are the same as DDS, just less intense.<ref>{{Archive|Site=web|URL=https://medlineplus.gov/genetics/condition/frasier-syndrome/}}</ref> It is seemingly rare, with only 50 reported cases, however CTF individuals with this variation may be overlooked.<ref>{{Archive|Site=web|URL=https://medlineplus.gov/genetics/condition/frasier-syndrome/#frequency}}</ref>
The flag was created on April 27, 2021 by FANDOM user Ariathatsme. The meaning goes as follows: Yellow for intersex spectrum, blue/grey for CTM individuals, pink/grey for CTF individuals, and white for unity and inclusivity.
== Frasier SyndromeCauses ==
This variation is caused when one ''WT1'' gene- a gene designed for connecting regions of DNA together- fails to properly function. Because of this, proteins that effect genitals and kidneys are effected during development in the womb.<ref>{{Archive|Site=web|URL=https://medlineplus.gov/genetics/condition/denys-drash-syndrome/#causes}}</ref>
'''Frasier Syndrome''' is an intersex condition that falls under DDS. It has the same cause (improper function of the ''WT1'' gene) however it is less severe. The symptoms are the same as DDS, just less intense.
P. Denys and Allan L. Drash first described the syndrome in 1967.<ref>{{Archive|Site=web|URL=https://en.wikipedia.org/wiki/Denys%E2%80%93Drash_syndrome#History}}</ref>
== Resources ==
<references />
* https://medlineplus.gov/genetics/condition/denys-drash-syndrome/#causes
* https://en.wikipedia.org/wiki/Denys%E2%80%93Drash_syndrome
*https://medlineplus.gov/genetics/condition/frasier-syndrome/#causes
[[Category:Intersex Traits]]
[[Category:TerminologyFlagless Sexes]]
[[Category:Verified Resources]]
[[Category:Sex Category]]
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