Anonymous user
no edit summary
(Adding categories) |
No edit summary |
||
Line 1:
'''De La Chapelle Syndrome''' (also known as '''XX Male Syndrome''' or '''46, XX Testicular Disorder''') is an [[intersex]] variation that effects one in every 20,000 [[AMAB]] or [[CTM]] births in which an individual has
Most with this variation [[Agenital|have small testicles or a missing testicle]] or a urethra opening that is on a unusual spot of the genitals ([[hypospadias]].) On rare occasion, one with this variation may have [[Ambiguous Genitalia|ambiguous genitals]]. Because of this, they may have [[AMAB Hypogonadism]].
In about 80% of individuals with De La Chapelle Syndrome, the variation results from an abnormal exchange of genetic material between chromosomes while they were forming in the uterus, which causes the individual to have no Y chromosomes, or only partial Y chromosomes.
Many with this variation tend to be shorter than average and infertile, however with testosterone treatments ([[Hormone Replacement Therapy|HRT]]) one may have a higher chance at a more natural flow of growth during puberty.<ref>https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/xx-male-syndrome</ref>
A similar intersex variation is [[SERKAL Syndrome]].
Line 12:
It is unknown when De La Chapelle Syndrome was discovered, however it has been recorded since 1987.
==
<references />
[[Category:Intersex Traits]]
[[Category:Flagless Sexes]]
|