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[[File:Aromatase Deficiency.jpg|thumb|Flag by Ariathatsme]] |
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'''Aromatase Deficiency''' is an [[intersex]] condition in which one has reduced levels of estrogen and increased levels of testosterone. Those with this condition often have [[Ambiguous Genitalia|ambiguous genitals]], are on the [[Agenital|agenital spectrum]], or have a [[Clitoromegaly|enlarged clitorous]]. It is unknown how common this condition is, however approximately 20 cases have been described in the medical literature. |
'''Aromatase Deficiency''' is an [[intersex]] condition in which one has reduced levels of estrogen and increased levels of testosterone. Those with this condition often have [[Ambiguous Genitalia|ambiguous genitals]], are on the [[Agenital|agenital spectrum]], or have a [[Clitoromegaly|enlarged clitorous]]. It is unknown how common this condition is, however approximately 20 cases have been described in the medical literature. |
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== Causes == |
== Causes == |
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The cause of this appears to be when there is a mutation in ones ''CYP19A1'' gene (the gene directly connected to an enzyme called aromatase, which controls estrogen and testosterone production.) Usually during fetal development, aromatase converts androgens/estrogens in the placenta, which is the link between the mother's blood supply and the fetus. This conversion in the placenta prevents androgens from directing sexual development in fetuses, which is what causes a long-term effect on the fetus's growth within it's parent. |
The cause of this appears to be when there is a mutation in ones ''CYP19A1'' gene (the gene directly connected to an enzyme called aromatase, which controls estrogen and testosterone production.) Usually during fetal development, aromatase converts androgens/estrogens in the placenta, which is the link between the mother's blood supply and the fetus. This conversion in the placenta prevents androgens from directing sexual development in fetuses, which is what causes a long-term effect on the fetus's growth within it's parent. |
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== Flag == |
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The flag was created on April 29, 2021 by FANDOM user [[User:Ariathatsme|Ariathatsme]]. The meaning goes as follows: green to represent how rare this condition is, grey to represent the negative effects from it, yellow for the intersex spectrum, blue-grey for CTM individuals and pink-grey for CTF individuals. |
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== Resources == |
== Resources == |
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