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Those with XX chromosomes ([[CTF]]) that have this variation often develop [[PCOS|ovarian cysts]] in early childhood, which causes a lack of production of eggs in the ovaries, which often causes them to have [[AFAB Hypogonadism]]. Because of this, they may have difficulty getting pregnant, or have a sporadic menstrual cycle. This also tends to cause a [[Secondary Sex Agenesis|lack of breast growth]] upon puberty, and excessive body hair.
Those with XY chromosomes ([[CTM]]) who have this variation often have infrequent sperm production and a decreased sex drive (unless they are already on the [[Asexual Spectrum|ace-spectrum]] and/or already not [[Sex-Favorable|sex-favorable]].) They may also have [[AMAB Hypogonadism|AMAB hypogonadism]].
Both [[AMAB]]/CTM and [[AFAB]]/CTF individuals with this variation seem to be abnormally tall, which causes thinner bones and a higher chance of injury due to the thin nature of the bones. They also tend to have high blood sugar, which causes them to gain weight and have a larger liver. This may classify them as physically [[disabled]] in some cases.
== Causes ==
The cause of this variation appears to be when there is a mutation in ones ''CYP19A1'' gene (the gene directly connected to an enzyme called aromatase, which controls estrogen and testosterone production.) Usually during fetal development, aromatase converts androgens/estrogens in the placenta, which is the link between the
== References ==
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