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[[File:Day6cyq-73f8f812-5cff-489c-86e2-f7d5facebd68.png|thumb|220x220px|The androgen insensitivity flag.]]
'''Androgen Resistance''' or '''Androgen Insensitivity Syndrome '''is a rare [[intersex]] trait affecting 1/20,000 to 1/64,000 [[AMAB]] or otherwise [[CTM]] individuals, causing one to be more resistant to androgens (such as testosterone.)<ref>
This can happen because of defects in the testicles or [[AMAB Hypogonadism|hypogonadism]]. This also can sometimes effect those with [[Ambiguous Genitalia|ambiguous genitalia]], as they may produce little to no testosterone.
▲This can happen because of defects in the testicles or [[AMAB Hypogonadism|hypogonadism]]. This also can sometimes effect those with [[Ambiguous Genitalia|ambiguous genitalia]], as they may produce little to no testosterone. In some cases, those with this variation may have vaginal traits, or may be on the [[agenital]] spectrum.<ref>https://medlineplus.gov/genetics/condition/androgen-insensitivity-syndrome/#causes</ref>
Those with CAIS are infertile. It is very rare for those with PAIS and MAIS to be capable of impregnating people.<ref>[https://my.clevelandclinic.org/health/diseases/22199-androgen-insensitivity-syndrome#:~:text=The%20most%20common%20symptom%20across,to%20make%20their%20partners%20pregnant. https://my.clevelandclinic.org/health/diseases/22199-androgen-insensitivity-syndrome#:~:text=The%20most%20common%20symptom%20across,to%20make%20their%20partners%20pregnant.]</ref>
▲This may also cause them to also fall under [[Aromatase Excess Syndrome|aromatase excess syndrome]].
==Complete Androgen Insensitivity Syndrome==
== Flag ==▼
'''Complete Androgen Insensitivity Syndrome (CAIS)''' is a subset of this variation, in which one with XY chromosomes has a complete inability for the cells to respond to androgen receptors. Those with CAIS look outwardly [[Müllerian|mullerian]], with a vagina and breasts. They may have [[Agenital|underdeveloped labia and/or clitoral hypoplasia.]] They have testicles that are either within the labia or within the inguinal ring.<ref>https://web.archive.org/web/20221225070702/https://en.wikipedia.org/wiki/Complete_androgen_insensitivity_syndrome#Signs_and_symptoms</ref>
The flag was coined by Pride-Flags on Deviantart, along with an anomynous user. It is made to resemble an orchid, as an orchid is a common symbol for intersex individuals.<ref>https://www.deviantart.com/pride-flags/art/Androgen-Insensitivity-Syndrome-662065442</ref>▼
Most do not have a uterus, cervix, or fallopian tubes, however in rare cases it does occur.
== References ==▼
==Partial Androgen Insensitivity Syndrome==
'''Partial Androgen Insensitivity Syndrome (PAIS)''' is a subset of this variation, in which one with XY chromosomes has a partial inability of the cell to respond to androgen receptors. Those with PAIS have a penis (possibly with [[hypospadias]], chordee, and/or a bifid scrotum), micropenis, [[clitoromegaly]], or ambiguous genitalia. Those with PAIS have testicles, with cryptorchidism being common. Some also experience mild breast growth. <ref>https://web.archive.org/web/20220916064816/https://en.wikipedia.org/wiki/Partial_androgen_insensitivity_syndrome</ref>
==Mild Androgen Insensitivity Syndrome==
'''Mild Androgen Insensitivity Syndrome (MAIS)''' is a subset of this variation, in which one with XY chromosomes has a mild inability for the cells to respond to androgen receptors. Those with MAIS appear mostly [[wolffian]], with a penis (sometimes with hypospadias) or micropenis. Some also experience mild breast growth. Those with this variation [[Secondary Sex Agenesis|will not develop many secondary sex traits]], however this is typically reversable through testosterone supplements ([[HRT]].)<ref>https://web.archive.org/web/20220916064820/https://en.wikipedia.org/wiki/Mild_androgen_insensitivity_syndrome#Signs_and_symptoms</ref>
▲The flag was coined by Pride-Flags on Deviantart, along with an anomynous user. It is made to resemble an orchid, as an orchid is a common symbol for intersex individuals.<ref>
<references />
[[Category:Article stubs]]▼
[[Category:Intersex Traits]]
[[Category:Pages With No History Section]]
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