×
Create a new article
Write your page title here:
We currently have 7,644 articles on LGBTQIA+ Wiki. Type your article name above or create one of the articles listed here!



    LGBTQIA+ Wiki
    7,644Articles

    45,X/46,XY Mosaicism: Difference between revisions

    Content added Content deleted
    m (Fixed categories)
    m (Archived resource.)
    Line 1: Line 1:
    [[File:Davpdjz-b7bb45df-a6c5-4a87-ace5-caa4ada3db71.png|thumb|220x220px|The 45,X/46,XY mosaicism pride flag.]]
    [[File:Davpdjz-b7bb45df-a6c5-4a87-ace5-caa4ada3db71.png|thumb|220x220px|The 45,X/46,XY mosaicism pride flag.]]
    '''45,X/46,XY Mosaicism '''or '''Mixed Gonadal Dysgenesis '''is a rare [[intersex]] variation affecting 1 in 15,000 individuals. It is a chromosomal karotype where some of one's cells have an X chromosome and some have XY chromosomes.<ref name=":0">https://pride-color-schemes.tumblr.com/post/161844110960/45x46xy-mosaicism</ref> Each case is different depending on the exact location and amount of X cells and XY cells in one's body.
    '''45,X/46,XY Mosaicism '''or '''Mixed Gonadal Dysgenesis '''is a rare [[intersex]] variation affecting 1 in 15,000 individuals. It is a chromosomal karotype where some of one's cells have an X chromosome and some have XY chromosomes.<ref name=":0">http://archive.today/YFp9r</ref> Each case is different depending on the exact location and amount of X cells and XY cells in one's body.


    Those with this variation who are [[CTM]] are typically shorter than usual, with a [[AMAB Hypogonadism|low output of testosterone]], and typically have a [[Agenital|micropenis]] (though they may have a common penis as well.)<ref>https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=1772</ref>
    Those with this variation who are [[CTM]] are typically shorter than usual, with a [[AMAB Hypogonadism|low output of testosterone]], and typically have a [[Agenital|micropenis]] (though they may have a common penis as well.)<ref>http://archive.today/viEzi</ref>


    For those with this variation who are [[CTF]] are typically born with vaginal aplasia, an [[Clitoromegaly|enlarged clitoris]], and may have only a single vaginal hole that connects both urinal output and sexual output.
    For those with this variation who are [[CTF]] are typically born with vaginal aplasia, an [[Clitoromegaly|enlarged clitoris]], and may have only a single vaginal hole that connects both urinal output and sexual output.
    Line 8: Line 8:
    Both CTM and CTF individuals with this variation tend to have [[Ambiguous Genitalia|ambiguous genitals]] as well.
    Both CTM and CTF individuals with this variation tend to have [[Ambiguous Genitalia|ambiguous genitals]] as well.


    One with this variation can have any internal sex organs, though asymmetrical gonads and other structures are common.<ref>https://www.cincinnatichildrens.org/health/m/mixed-gonadal-dysgenesis</ref> Depending on how the gonads develop, the output of estrogen and testosterone may vary, however it is common that those with this variation tend to have a [[masculine]] puberty, making CTF individuals with this variation possibly also have [[hyperandrogenism]].
    One with this variation can have any internal sex organs, though asymmetrical gonads and other structures are common.<ref>http://archive.today/FqxBS</ref> Depending on how the gonads develop, the output of estrogen and testosterone may vary, however it is common that those with this variation tend to have a [[masculine]] puberty, making CTF individuals with this variation possibly also have [[hyperandrogenism]].


    == History ==
    == History ==
    The earliest mention of Mixed Gonadal Dysgenesis appears to have been in 1992, with Richard E. Behrman in the 14th edition of the Nelson textbook of Pediatrics.<ref>http://www-personal.umd.umich.edu/~jcthomas/JCTHOMAS/1997%20Case%20Studies/N.Justus.html</ref>
    The earliest mention of Mixed Gonadal Dysgenesis appears to have been in 1992, with Richard E. Behrman in the 14th edition of the Nelson textbook of Pediatrics.<ref>http://archive.today/EUT8</ref>


    == Flag ==
    == Flag ==
    Cookies help us deliver our services. By using our services, you agree to our use of cookies.
    Cookies help us deliver our services. By using our services, you agree to our use of cookies.