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Line 6: For those with this variation who are [[CTF]] are typically born with vaginal aplasia, an [[Clitoromegaly\|enlarged clitoris]], and may have only a single vaginal hole that connects both urinal output and sexual output. Both CTM and CTF individuals with this variation tend to have [[Ambiguous Genitalia\|ambiguous genitals]] as well. Infertility is common with this variation.<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926925/</ref> One with this variation can have any internal sex organs, though asymmetrical gonads and other structures are common.<ref>{{Archive\|URL=2022.02.11-103457/https://www.cincinnatichildrens.org/health/m/mixed-gonadal-dysgenesis}}</ref> Depending on how the gonads develop, the output of estrogen and testosterone may vary, however it is common that those with this variation tend to have a [[masculine]] puberty, making CTF individuals with this variation possibly also have [[hyperandrogenism]].